Journal of Case Reports and Reviews in Medicine (ISSN: 3069-0749)
Open Access | DOI: 10.64978/JCRRM
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Management of Statin Intolerance and Combined Dyslipidemia with a Monacolin K-Free Nutraceutical Formulation (LopiGLIK® BIO): A Clinical Case Report

B. Trimarco*

Received : September 30, 2026 | Published : October 07, 2026

Citation: Trimarco B. Management of Statin Intolerance and Combined Dyslipidemia with a Monacolin K-Free Nutraceutical Formulation (LopiGLIK® BIO): A Clinical Case Report. J Case Rep Rev Med. 2026;2(4):1-2. doi: 10.64978/jcrrm.2026.10070134

Copyright: © 2026 The Author(s). Published by SCIVOLVE.

License: This article is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0) , which permits use, sharing, adaptation, distribution, and reproduction in any medium or format, provided appropriate credit is given to the original author(s) and the source, a link to the Creative Commons licence is provided, and any changes made are indicated.

Abstract

Statin intolerance represents a significant clinical challenge in cardiovascular disease prevention, often leading to therapy discontinuation and uncontrolled lipid levels. Monacolin K-free nutraceuticals provide an alternative therapeutic strategy for lipid and glucose management without statin-related side effects. We report the case of a 58-year-old male with moderate hypercholesterolemia, impaired fasting glucose, and a history of statin-associated muscle symptoms (SAMS). After discontinuing statin therapy due to severe myalgia and elevated creatine kinase levels, the patient was started on a daily oral formulation of LopiGLIK® BIO — a nutraceutical containing Trigonella foenum-graecum (fenugreek), Morus alba, and Niacin. After 12 weeks of treatment, the patient showed a significant improvement in lipid levels, with a 22% reduction in low-density lipoprotein cholesterol (LDL-C) and a 19% reduction in total cholesterol, along with stabilized fasting plasma glucose, without experiencing any muscular or gastrointestinal adverse effects. This case highlights the clinical utility and safety of a monacolin K-free nutraceutical combination in managing cardiovascular risk in statin-intolerant patients.

Keywords: Statin Intolerance; Dyslipidemia; LopiGLIK BIO; Nutraceuticals; Fenugreek; Morus alba; Monacolin K-free.

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