Journal of Case Reports and Reviews in Medicine (ISSN: 3069-0749)

Vaccine Hesitancy: A Ticking Time Bomb

Yusuf Ishaya Dogonzo, Ekoh Charles Obinna, Raihanatu Muhammad Baba, Christopher Chimaobi Onyeabor, Clifford Liki Barnabas

Received : September 28, 2025 | Published : October 27, 2025

Citation: Dogonzo YI, Obinna EC, Baba RM, Onyeabor CC, Barnabas CL. Vaccine Hesitancy: A Ticking Time Bomb. J Case Rep Rev Med. 2025;1(4):1-8. DOI: 10.64978/jcrrm-0105

Abstract

The rise in cases of vaccine hesitancy is becoming a global threat to tackling emerging public health challenge such as pandemics. This study aims to investigate the prevalence and underlying factors fuelling vaccine hesitancy within Nigerian population. The study focuses on young adults of school age below 25 years due to factors including critical developmental stage of human beings, familiarity with technology and propensity to explore and make independent decisions. The study adopted a cross-sectional survey design and utilized qualitative data obtained from responses of individuals for analysis. The findings revealed that, despite the general acknowledgement of the efficiency of previous vaccines, a significant proportion of the respondent were not vaccinated against COVID-19. Factors including lack of trust in government and scientific institutions, widespread misinformation about the vaccine and impact of religion and traditional beliefs were identified as the primary drivers of hesitancy. A striking observation is that the challenge public health institutions may face in tackling future pandemics will be not just combating the pathogens but also convincing a great section of the population to accept the vaccine. In conclusion, this study suggests that vaccine hesitancy, a biological challenge that is gradually changing to a societal and behavioural challenge must be carefully addressed before the next pandemic strikes.